| Seattle |
| Passing: | Matt Hasselbeck 25/34 (198 YDS) |
| Rushing: | Julius Jones 20 CAR (67 YDS) |
| Receiving: | Nate Burleson 5 REC (54 YDS) |
|
| San Francisco |
| Passing: | Alex Smith 27/45 (310 YDS) |
| Rushing: | Frank Gore 9 CAR (25 YDS) |
| Receiving: | Vernon Davis 6 REC (111 YDS) |