Cubs 11, Pirates 10 (12 innings)
CHICAGO -- Matt Szczur's one-out base hit in the 12th inning drove home Starlin Castro from third with a game-winning run as the Chicago Cubs claimed an 11-10 walk-off victory over the Pittsburgh Pirates on Friday.
Szczur sent a routine fly to shallow right field that dropped for a hit after Pirates right fielder Gregory Polanco tripped and fell, giving the Cubs their fourth walk-off win this season.
The Cubs had bases loaded with one out in the bottom of the 12th after Pirates right-hander Radhames Liz intentionally walked outfielder Jorge Soler.
The Cubs ran their winning streak to five while the Pirates dropped their third in-a-row.
The game, which lasted 5 hours and 1 minute, featured 21 combined runs and 30 hits while 16 pitchers were used.
The Cubs led most of the way until Pittsburgh forced a 10-10 ninth inning tie on catcher Francisco Cervelli's two-out single that drove in third baseman Josh Harrison.
Starters Kyle Hendricks (Cubs) and Jeff Locke (Pirates) did not figure in decision.
Cubs right-hander Edwin Jackson (2-1) worked one inning for the win while Liz, who pitched just 1/3 inning, suffered the loss.
Rookie third baseman Kris Bryant broke a scoreless tie in the third, driving in center fielder Dexter Fowler and first baseman Anthony Rizzo with his fourth homer of the season.
Pirates first baseman Pedro Alvarez' solo homer broke the shutout in the fourth with his fifth homer.
The Cubs made it 5-1 in the bottom of the inning.
Fowler's one-out sacrifice to left drove in Hendricks, who reached on a lead-off double. Rizzo then hit his eighth homer of the year to left to bring home Fowler.
That was it for Locke, who threw 102 pitches in 3 2/3 innings. He was replaced by newly-activated Antonio Bastardo, who closed out the frame.
The Cubs extended the lead to 7-1 as Pirates right-hander Rob Scahill allowed two runs in the fifth. Szczur's single to left drove in Castro and catcher Welington Castillo.
Locke gave up five runs on six hits, walked three and struck out four.
Cervelli doubled home three runs as part of a four-run Pirates sixth that spelled the end for Hendricks.
Right-handed reliever Justin Grimm gave up another as pinch hitter Corey Hart drove in Cervelli.
Center fielder Andrew McCutchen flew out to finally end the sixth.
Cubs right fielder Jorge Soler made it 8-5 in the bottom of the inning with a two-out single that scored Bryant from second. Rizzo's one-out base hit in the seventh drove home second baseman Addison Russell for a 9-5 lead while Bryant's sacrifice to deep center scored Fowler to make it 10-5.
But the Pirates weren't through as Harrison slammed a lead-off solo home run in the eighth off right-hander Jason Motte, cutting the Cubs lead to 10-6.
McCutcheon then hit his fourth home run of the season, a three-run shot off right-hander Pedro Strop that cut the Chicago lead to 10-9.
NOTES: Pirates RHP Charlie Morton worked seven innings in a rehab start at Triple-A Indianapolis on Thursday. He allowed two runs (one earned) on 11 hits while walking none and striking out eight. He is due to arrive in Chicago on Saturday and could come off the 15-day disabled list this weekend. ... RHP Gerrit Cole (5-1, 2.32 ERA) goes against Cubs LHP Jon Lester (3-2, 4.10 ERA) in Saturday's middle game. ... Elias Sports Bureau reports that the Cubs' 6-5 win over the Mets on Thursday was just the third time in the last three seasons that the Cubs won a game after trailing by four or more runs. They were down 5-1 at one point. ... Cubs 2B Addison Russell saw his streak of 16 straight games reaching base safely come to an end in that Thursday game.