Total fantasy points here does take into account special teams. However, my primary focus when ranking defenses is points against, yards against and forced turnovers. Some of the defenses you see on this list might not actually be among the best overall units in the league. Of course that's just reality, and this is fantasy. As you already know, fantasy is the best of both worlds...In sports or not.
But, I digress.
Here is your top-10 defenses through the first five weeks of the 2012 NFL regular season.
| Team | PPG | YPG | Turnovers | Points |
| 1. Chicago Bears | 15.6 | 291.2 | 17 | 92 |
| 2. San Francisco 49ers | 13.6 | 262.6 | 10 | 53 |
| 3. Houston Texans | 14.6 | 275.6 | 11 | 64 |
| 4. Seattle Seahawks | 14.0 | 258.6 | 7 | 58 |
| 5. Arizona Cardinals | 15.6 | 334.0 | 11 | 53 |
| 6. Minnesota Vikings | 15.8 | 304.2 | 7 | 58 |
| 7. St. Louis Rams | 18.8 | 335.4 | 9 | 47 |
| 8. Dallas Cowboys | 22.0 | 277.5 | 4 | 24 |
| 9. Pittsburgh Steelers | 23.0 | 295.8 | 6 | 24 |
| 10. Philadelphia Eagles | 19.8 | 307.2 | 7 | 27 |