Cardinals at 49ers

The Arizona Cardinals have been plagued by turnovers of late and the trendy preseason Super Bowl pick temporarily could be faced with turning over the keys to backup quarterback Drew Stanton on Thursday when they visit the San Francisco 49ers. With veteran Carson Palmer considered day-to-day with a concussion, Stanton may be left looking to conjure the magic that saw him pull a 5-3 mark out of his hat during a stint in 2014.

Stanton struggled mightily in taking over for the concussed Palmer on Sunday, completing just 4-of-11 passes in a 17-13 setback to Los Angeles and his two interceptions upped Arizona's turnover total to nine during its two-game skid. "I'll say this, I never envisioned this type of start," Cardinals general manager Steve Keim told Arizona Sports 98.7 FM. "I don't know that anybody -- fans or anybody in the organization -- would have envisioned this." The 49ers had no such issue with the Rams with a 28-0 season-opening shellacking, but the defense of Chip Kelly's club summarily has been shredded to the tune of 458.3 yards and 35.7 points per contest during its three-game losing streak. To add injury to insult, four-time NFL All-Pro linebacker NaVorro Bowman sustained a torn left Achilles in Sunday's 24-17 setback to Dallas and will miss the rest of the season.

TV: 8:25 p.m. ET, NFL Network. LINE: Cardinals -3. O/U: 42.5

ABOUT THE CARDINALS (1-3): David Johnson (64 carries, 300 yards, three TDs) leads the NFL with 510 yards from scrimmage and has recorded 100 or more total yards in all four contests this season and eight of his last nine games. Johnson amassed 124 from scrimmage (83 rushing, 41 receiving) versus the Rams, but the workload was decidedly different in last year's season series with San Francisco (15 carries, 46 yards). The 24-year-old will be spelled by Andre Ellington, as veteran Chris Johnson (groin) was placed on injured reserve Tuesday. Tyvon Branch was also shuffled to IR, with fellow safety Tyrann Mathieu temporarily being moved into the slot while D.J. Swearinger plays in nickel packages.

ABOUT THE 49ERS (1-3): San Francisco collected eight takeaways in its first three games to provide a helping hand for the NFL's 28th-ranked offense, which scored a league-best 45 points off the turnovers after mustering an NFL-worst 25 for the entire 2015 season. The 49ers failed to force a turnover versus the Cowboys on Sunday and Blaine Gabbert's fourth interception of the season ended his team's bid for an upset. Carlos Hyde (73 carries, 299 yards, NFC-best five TDs) is averaging 4.9 yards per rush over his last two games, but was limited to just 51 yards in a 47-7 loss at Arizona on Sept. 27.

EXTRA POINTS

1. Arizona has yet to score in the first quarter this season and has been blanked over the first 15 minutes of a contest in six straight dating to 2015.

2. San Francisco WR Jeremy Kerley, who had six receptions for 88 yards and a touchdown last week, leads the team in catches (18) and receiving yards (202).

3. Cardinals LBs Chandler Jones and Markus Golden each have recorded a sack in all four contests this season.
Poll

Who will win this game?

Odds
SpreadMoneylineMoneyTotal
San Francisco 49ers49ers0  155600
49.50
o 115u -154
Arizona CardinalsCardinals0  -300-1600
Spread Consensus: San Francisco 49ers: 43.94%     Arizona Cardinals: 56.06%
Vegas Prediction: San Francisco: 25 (Tie)    Arizona: 25 (Tie)
Season Series
San FranciscoStatsArizona
1-3Vs3-1
54Points106
6Touchdowns12
4/5Field Goals7/7
78/118 (779 yd.)Passing86/146 (1127 yd.)
102 CAR (458 yd.)Rushing118 CAR (391 yd.)